Product Description
Product Description
Gentamicin is a bactericidal antibiotic with activity against Gram-negative bacteria, used to treat bacterial infections. It was made from Micromonospora purpurea. Gentamicin works by irreversibly binding the 30S subunit of the bacterial ribosome, inhibiting its protein synthesis.
BSA (bovine serum albumin) is conjugated to gentamicin (1: 139-148). One or more of the four amine groups in gentamicin are directly linked to carboxyl group(s) in BSA. Gentamicin has a molecular weight of 477.6 Da and BSA has a molecular weight of 66.4 kDa. The resultant conjugation solution is then buffer-exchanged with 20 mM PBS at a pH of 7.4.
Conjugated BSA-gentamicin is used to recognize gentamicin-specific antibodies by ELISA and lateral flow based immunoassay.
